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MediciNova asthma drug fails trial; shares crash
Reuters
MediciNova, which is testing MN-221 as a treatment for acute asthma attacks not responsive to standard therapy, said the drug failed to show a statistically significant improvement over a placebo. MN-221 looks to treat the condition by bypassing ...
MediciNova Reports Results of a Phase 2b Clinical Trial of MN-221 in Asthma ...FierceBiotech
MediciNova study doesn't yield significant resultsMarketWatch
MediciNova Misses Primary Goal in Mid-Stage Trial of IV Asthma DrugXconomy

all 28 news articles »

Biologic Works in Ulcerative Colitis
MedPage Today
At 6 weeks, 47.1% of patients receiving vedolizumab had achieved a clinical response, compared with 25.5% of those randomized to placebo (P<0.0001), said Brian G. Feagan, MD, of Robarts Research Institute in London, Ontario, in a late-breaker session ...
Takeda drug impresses in ulcerative colitis studyReuters

all 2 news articles »

MyFox Philadelphia

New Phase 3 data for Tradjenta® (linagliptin) tablets in black or African ...
MarketWatch (press release)
[4] In the 24-week study, 226 patients were randomized (106 to linagliptin, and 120 to placebo)[1], and received at least one dose of the study drug in order to be included in the safety analyses.[1] Patients who had a measurement of A1C at baseline ...
Lilly Optimistic on Type-2 Diabetes Drug for Black PatientsFox Business
Boehringer Ingelheim announces diabetes trial dataMass High Tech
Lilly, BI diabetes drug shows greater A1C reduction in African-American adults ...Drug Store News
RTT News
all 23 news articles »

Marijuana for MS: panacea or placebo?
Examiner.com
This study attempted to clinically measure efficacy in a placebo-controlled trial. The lead author of the study, Jody Corey-Bloom, MD, PhD, from the University of San Diego says there is a trade-off. Both spasticity and pain were reduced in the ...


Efficacy of low power laser therapy in fibromyalgia: a single-blind, placebo ...
Chiropractic Economics
A randomised, single-blind, placebo-controlled study was conducted to evaluate the efficacy of low-energy laser therapy in 40 female patients with fibromyalgia. Patients with fibromyalgia were randomly allocated to active (Ga-As) laser or placebo laser ...


Colitis Responds to Anti-TNF Therapy
MedPage Today
SAN DIEGO -- Patients with ulcerative colitis treated with golimumab, a tumor necrosis factor (TNF) inhibitor, had robust clinical responses compared with placebo, researchers reported here. At week six of treatment, clinical responses were seen in ...
J&J's Simponi Helps Colitis Patients In Clinical TrialWall Street Journal
Patients with ulcerative colitis respond to Simponi, study findsDrug Store News
New Phase 3 Study Results Show Anti-TNF SIMPONI® Induced Clinical Response in ...PR Newswire (press release)
Zenopa
all 11 news articles »

Aspirin Found To Prevent Recurrent Venous Thromboembolism
Forbes
Following 6 to 18 months of oral anticoagulation, 403 patients with first-time unprovoked VTE were randomized to aspirin (100 mg daily) or placebo for two years. Aspirin therapy resulted in a significant reduction in VTE but did not cause an increase ...
Aspirin May Reduce Risk of Repeat Blood ClotsWebMD

all 2 news articles »

Soy supplement shows no blood pressure benefit
Reuters
'DISAPPOINTING' RESULTS So for their study, Wong and his colleagues randomly assigned 24 menopausal women to take either soy isoflavones or placebo tablets for six weeks. The supplement gave a daily dose of 80 milligrams of isoflavones.

and more »

Topical Drug May Hit the Spot for Female Arousal
MedPage Today
Symptoms of female sexual arousal disorder (FSAD) improved significantly during treatment with a topical prostaglandin (alprostadil) compared with placebo. Note that younger women (<45) treated with the highest concentration of the medication had the ...


Shire Presents Data on Venvanse
Zacks.com
In this phase III double-blind, placebo-controlled, randomized study, long-term maintenance of efficacy and safety of Venvanse in children and adolescents aged 6 to 17 years with moderately symptomatic ADHD was evaluated. Significantly less treatment ...
Efficacy of Shire's Vyvanse maintained in ADHD adolescents after at least six ...The Pharma Letter

all 4 news articles »

Lilly's GLP-1 Agonist Delivers
Zacks.com
Results from the phase II, randomized, double-blind, placebo-controlled, 26-week, parallel study showed that dulaglutide achieved non-inferiority after 16 weeks for mean 24-hour systolic blood pressure (SBP). Two doses (0.75 mg and 1.5 mg) of ...
Lilly Diabetes Presents Phase II Blood Pressure?Pharmaceutical Processing
Eli Lilly's diabetes drug meets mid-stage trial goalReuters
Dulaglutide passes BP hurdle, but heart-rate increase observedTheHeart.Org
Wall Street Journal
all 33 news articles »

Aspirin Cuts Recurrent VTE After Stopping Warfarin
MedPage Today
This study found a marked reduction in recurrent venous thromboembolism among patients with unprovoked events who were randomly assigned to either aspirin (100 mg daily) or placebo and were followed for 2 years. Aspirin reduced recurrent venous ...
Aspirin May Prevent Recurrence of Deep Vein Blood ClotsU.S. News & World Report
Aspirin Effective in Preventing Thromboembolism RecurrenceDoctors Lounge

all 11 news articles »

Zee News

Vitamin C can help pregnant smokers
WBRC
Researchers found that newborns of smoking women who took a Vitamin C supplement had better lung function compared with newborns of smoking women who received a placebo. Most health advice has us feeling guilty over our indulgences.
For pregnant smokers who can't quit, an Oregon study tests vitamin COregonLive.com
Babies of smoking moms get help from vitamin CJakarta Post
Pregnant smokers should take vitamin CABC2 News
EmpowHer -Medical Xpress
all 26 news articles »

Antibiotic Cuts Flare-Ups in Bronchiectasis
MedPage Today
A small randomized trial found that low-dose erythromycin significantly decreased exacerbations compared to placebo in patients with bronchiectasis not caused by cystic fibrosis. Note that oral streptococci increased in resistance to macrolides in the ...


Data for Amarin's AMR101 to be Presented at the National Lipid Association ...
MarketWatch (press release)
The second poster is titled "A Phase 3, Multicenter, Placebo-Controlled, Randomized, Double-Blind, 12-Week Study to Evaluate the Effect of Two Doses of AMR101 on Fasting Serum Triglycerides and Other Lipid Parameters in Statin-Treated Patients with ...

and more »

Voice of America

Clinical Trials for Alzheimer's Disease Preventative Drug to Begin Early 2013
Santa Barbara Independent
The study involves testing candidates for the genetic mutation, taking a record of baseline conditions, administering either the medication or a placebo over a period of time, and monitoring the subjects' progress. In this double-blind trial, ...
A Campaign Against Alzheimer's DiseaseVoice of America
U.S. Government Sets Out Alzheimer's PlanScientific American

all 3 news articles »

Takeda drug impresses in ulcerative colitis study
Chicago Tribune
The biologic drug, vedolizumab, met the goals of the Phase III trial with highly statistically significant advantages in rates of remission, clinical response and bowel healing compared with a placebo, researchers said. Of the patients taking part in ...
Vedolizumab Scores on Safety, Efficacy for Ulcerative ColitisFamily Practice News Digital Network

all 7 news articles »

PR Web

Steroids Help Unfreeze Bell's Palsy
MedPage Today
They ranged in age from 18 to 75 and were enrolled at 17 public referral centers involved in the Swedish and Finnish Scandinavian Bell's Palsy Study, a prospective, randomized, double-blind, placebo-controlled, multicenter trial.
'Prednisolone's Considerable Effect On Bells Palsy Symptoms'Medical News Today
New Study Reports Prednisolone Significantly Reduces Lasting Effects of Bell's ...PR Web (press release)

all 4 news articles »

Lilly's GLP-1 Agonist Delivers
Daily Markets
Results from the phase II, randomized, double-blind, placebo-controlled, 26-week, parallel study showed that dulaglutide achieved non-inferiority after 16 weeks for mean 24-hour systolic blood pressure (SBP). Two doses (0.75 mg and 1.5 mg) of ...
Lilly posts clean safety data on PhIII diabetes blockbuster hopefulFierceBiotech

all 4 news articles »

Novartis lung drug superior to placebo over 1 year
Chicago Tribune
ZURICH (Reuters) - A Novartis experimental lung drug to treat smokers' cough was superior to a placebo in improving lung function over a one-year period and had similar efficacy to a rival drug from Pfizer and Boehringer Ingelheim, the Swiss drugmaker ...
Novartis NVA237 Phase III data showed rapid, sustained improvement in lung ...Reuters
NVA237 Phase III GLOW2 Data at American Thoracic Society (ATS) International ...MarketWatch (press release)
New Novartis COPD drug beats placebo over a yearPharma Times
PMLiVE
all 35 news articles »


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